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Andy Chevigné and his group, RTI-5152-12 is postulated to boost the amounts of opioid peptides that bind to classical opioid receptors in the brain, causing heightened painkilling action. The LIH-RTI study groups set up a collaboration arrangement and submitted a joint patent application in December 2020.The opioid technique within the human physi
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2015). These reports, taken jointly, propose that, While a direct activation of GPR55 or PPAR‐α occurs, PEA can create its anti‐inflammatory action within the gut also by using indirect activation of CB1 and CB2 receptors, most likely due to the ability of the compound to potentiate the motion of endocannabinoids at these receptors.Costa and c